自适应神经-模糊推理系统的混合协同微粒群算法进化设计

在分析自适应神经-模糊推理系统(ANFIS)结构和参数特点的基础上,定义一个布尔向量L作为网络的结构参数,与原来ANFIS的前件参数集一起构成了新的前件参数集{c,σ,L},并给出了一个新的网络输入输出关系表达式.针对该输入输出表达式,提出一种用于优化ANFIS前件参数集的混合协同微粒群算法.该将参数集L和{c,σ}分别放在两个子微粒群并根据各自不同的特点应用二进制PSO和GCPSO算法进化,两个子微粒群之间的协同由定义的一个协同函数实现,而网络的结论参数依旧用最小二乘法进行优化.应用该算法进行ANFIS网络结构和隶属函数参数的自适应设计,在Henon映射产生的混沌时间序列预测中显示了良好的性能.     

江苏农村居民收入差距、消费差异与消费潜力研究———基于江苏农村细化SAM的乘数分析

在所建立的2002年江苏农村居民消费细化社会核算矩阵(Social Accounting Matrix,SAM)的基础上,通过SAM乘数的分解,从不同商品及服务消费和不同收入分组两方面对江苏农村居民消费净开放效应进行分析,并将账户乘数和固定价格乘数效应进行了比较分析.主要研究结论:第一,居住、食品和交通通讯是目前江苏农村居民的消费热点,但教育文化娱乐、衣着和医疗保健消费重视程度不足;第二,除最高收入户外,江苏各收入阶层对家庭设备及服务具有较大的消费欲望,消费潜力巨大;第三,中低收入及以下收入阶层对医疗保健和教育文化娱乐消费欲望非常强烈,政府应该在相关福利政策上给予一定支持,以促进这两类消费的良性发展;最后,为继续保持江苏农村居民交通通讯的发展,政府仍然有必要加强农村交通通讯基础设施建设,从而改变居民消费行为.     

基于神经网络的布图设计产业化前景评估

给出了集成电路布图设计产业化前景的评价指标体系,并通过构建前馈神经网络专家系统,对集成电路布图设计的产业化前景进行综合分析。该指标体系和专家系统较好地解决了对集成电路布图设计的产业化前景进行综合分析的问题。选择17个集成电路布图进行了实例分析,对比分析的结果表明该系统具有强大的计算与学习能力,能迅速快捷地判断布图设计的产业前景。     

模切流水线的整体设计

提出了圆压圆模切流水线总体工艺方案的设计思路,针对模切技术的发展现状,对流水线的主要装置进行了再设计,既节约了生产成本,又确保了印刷质量.设计过程中采用大型商用软件实现三维建模和动态模拟,提高了设计效率,缩短了产品制备周期,具有重大的工程应用价值和社会效益.     

Immune responses of a designed HIV-1 DNA vaccine on rhesus monkeys

According to the UNAIDS/WHO report (http:// www.unaids.org/Epi2005/doc/report.html), there are about 40.3 million HIV/AIDS survivors, and the new HIV infection number amounts to about 4.9 million, while the death number is some 3.1 million in the world in…     

Construction and anti-tumor effects of recombinant fowlpox virus expressing Newcastle disease virus hemagglutinin-neuramidinase gene

Hemagglutinin-neuramidinase (HN), a Newcastle disease virus-derived protein, not only mediates receptor recognition but also possesses neuraminidase (NA) activity, the ability to cleave a component of those receptors, N-acetylneuraminic acid (NAcneu, sialic acid). It is known that this protein in mammalian species, including human beings, has interesting anti-neoplastic as well as immune stimulating properties. To explore the use of the HN gene in cancer gene therapy, we constructed a recombi-nant fowlpox virus expressing the HN protein (vFV-HN) and compared the anti-tumor activity of the recombinant virus with that of wild-type fowlpox virus (FPV) in vivo and in vitro. Here we found that although B16 cells were somewhat resistant to the basal cytotoxic effect of wild-type fowlpox virus, infection with vFV-HN caused a pronounced cytotoxic effect and, the survival of tumor-bearing mice immunized with vFV-HN was significantly increased compared with the survival of mice immunized with the FPV alone. Furthermore, the immunization of mice with vFV-HN elicited a B16 tumor-specific cytotoxic T lymphocyte (CTL) response and clonal expansion of both CD4 and CD8 T cell populations in vivo. In addition, T cells from lymph nodes of mice vaccinated with vFV-HN secreted high levels of the Th1 cytokine IL-2 and IFN-γ, indicating that the regression of tumor cells is related to a Th1-type dominant immune response. These results demonstrate that vaccination with vFV-HN may be a potential strategy for cancer gene therapy.     

A new type of triploid crucian crap?red crucian carp (♀)×allotetraploid (♂)

A new type of triploid hybrids (TC) was produced by crossing red crucian carp (♀) with allotetraploid hybrids (♂). This type of triploids with no barbel was spindle-shaped and gray in color. Compared with their parents, some data of the morphological traits in the triploid hybrids were intermediate to those of their parents, and some were beyond their parents with heterozygous traits. Under the same culture conditions, the growth rate of the new type triploids was faster than their maternal red crucian carp (RC). The gonadal development of triploids was obviously slower than that of diploids, and the germ cells in them were degenerated. Compared with another type of triploids produced by Japanese crucian carp (♀) with allotetraploid hybrids (♂), the new type triploids not only kept faster growth rate and sterility, but also had no barbel that was similar to the common carp. The absence of the barbel in the new type of triploids has the important significance in both the inheritance and fish breeding.     

基于查找表的功放线性预失真方法研究

在无线通信系统中,高功率放大器因其具有非线性特性,会导致频谱再生和邻道干扰等问题。为克服这一特征,采用一种基于查找表的自适应预失真方法。首先对查找表进行初始化,再采用自适应算法实时更新查找表内容,从而有效消除功放的非线性失真。仿真实验表明,该自适应预失方法可降低互调失真(IMD),能有效提高功放线性度,从而提高系统性能。     

Subsumption Checking between Concept Queries in Different Ontologies Based on Mutual Instances

This paper proposes a checking method based on mutual instances and discusses three key problems in the method： how to deal with mistakes in the mutual instances and how to deal with too many or too few mutual instances. It provides the checking based on the weighted mutual instances considering fault tolerance, gives a way to partition the large-scale mutual instances, and proposes a process greatly reducing the manual annotation work to get more mutual instances. Intension annotation that improves the checking method is also discussed. The method is practical and effective to check subsumption relations between concept queries in different ontologies based on mutual instances.     

一种适用于教学的酶联免疫吸附试验的抗原抗体系统制备

目的:探讨设计一种教学成本低、便于教学使用、有助于培养医学生综合实验设计能力和提高实验基本操作技能的酶联免疫吸附实验抗原抗体系统.方法:以提纯的人IgG免疫家兔获取兔抗人IgG抗体,再用其包被酶标反应板,以人血清(人IgG)作抗原,用酶标记羊抗人IgG抗体结合抗原及催化底物显色反应.结果:该双抗体夹心法,底物显色反应清楚肉眼即可作出判定,非特异干扰极小.结论:我们设计的酶联免疫吸附实验-双抗体夹心法原理清晰、便于理解和掌握、教学成本较低、结果易于观察、便于教学大量使用.